Product Name :
1-(3-Carboxypropyl)-3,7-dimethylxanthine (CAS 6493-07-8)
Synonym :
Application :
1-(3-Carboxypropyl)-3,7-dimethylxanthine is a metabolite of Pentoxifylline
CAS:
6493-07-8
Purity:
Molecular Weight:
266.25
Formula :
C11H14N4O4
Physical state:
Solid
solubility :
Soluble in DMSO
Shipping Condition :
Store at -20° C
Melting point:
208-210°C (lit.)
SMILES:
CN1C=NC2=C1C(=O)N(C(=O)N2C)CCCC(=O)O
References:
:Pentoxifylline and its major oxidative metabolites exhibit different pharmacological properties.1445086-17-8 site | Fantin, M., et al. 2006. Eur J Pharmacol. 535: 301-9. PMID: 16545799A comparison of human pharmaceutical concentrations in raw municipal wastewater and yellowwater. | Winker, M., et al. 2008. Sci Total Environ. 399: 96-104. PMID: 18455216Bioanalysis of pentoxifylline and related metabolites in plasma samples through LC-MS/MS. | Sora, DI., et al. 2010. Biomed Chromatogr. 24: 663-74. PMID: 19810007Global mass spectrometry based metabolomics profiling of erythrocytes infected with Plasmodium falciparum. | Sana, TR., et al. 2013. PLoS One. 8: e60840. PMID: 23593322Pentoxifylline and its applications in dermatology. | Hassan, I., et al. 2014. Indian Dermatol Online J. 5: 510-6. PMID: 25396144Urinary excretion of pentoxifylline and its metabolites by standardbred mares. | Kwong, EC., et al. 1989. Can J Vet Res. 53: 147-53. PMID: 2713780Safety, tolerability, and pharmacokinetics of the novel pan-phosphodiesterase inhibitor ZSP1601 in healthy subjects: a double-blinded, placebo-controlled first-in-human single-dose and multiple-dose escalation and food effect study. | Zhu, X., et al. 2021. Expert Opin Investig Drugs. 30: 579-589. PMID: 33682556A risk based assessment approach for chemical mixtures from wastewater treatment plant effluents.85073-19-4 Molecular Weight | Finckh, S.PMID:33730164 , et al. 2022. Environ Int. 164: 107234. PMID: 35483182Effects of pentoxifylline on sputum neutrophil elastase and pulmonary function in patients with cystic fibrosis: preliminary observations. | Aronoff, SC., et al. 1994. J Pediatr. 125: 992-7. PMID: 7996376The effects of oral pentoxifylline on the cytokine release syndrome during inductive OKT3. | DeVault, GA., et al. 1994. Transplantation. 57: 532-40. PMID: 8116037Diltiazem and pentoxifylline determination in postmortem specimens. | Engelhart, DA., et al. 1997. J Anal Toxicol. 21: 576-9. PMID: 9399129