Product Name :
2-Hydroxy Trimipramine (CAS 2064-15-5)
Synonym :
Application :
2-Hydroxy Trimipramine is A Trimipramine metabolite
CAS:
2064-15-5
Purity:
98%
Molecular Weight:
310.43
Formula :
C20H26N2O
Physical state:
Solid
solubility :
Shipping Condition :
Store at -20° C
Melting point:
62-67° C
SMILES:
CC(CN1C2=C(CCC3=CC=CC=C31)C=C(C=C2)O)CN(C)C
References:
:Enantiomers′ potential in psychopharmacology–a critical analysis with special emphasis on the antidepressant escitalopram. | Baumann, P., et al. 2002. Eur Neuropsychopharmacol. 12: 433-44. PMID: 12208561Influence of quinidine on the pharmacokinetics of trimipramine and on its effect on the waking EEG of healthy volunteers. A pilot study on two subjects. | Eap, CB., et al. 1992. Neuropsychobiology. 25: 214-20. PMID: 1454163Trimipramine pharmacokinetics after intravenous and oral administration in carriers of CYP2D6 genotypes predicting poor, extensive and ultrahigh activity. | Kirchheiner, J., et al. 2003. Pharmacogenetics. 13: 721-8. PMID: 14646691The impact of the CYP2D6-polymorphism on dose recommendations for current antidepressants. | Thuerauf, N. and Lunkenheimer, J. 2006. Eur Arch Psychiatry Clin Neurosci. 256: 287-93. PMID: 16783493Inhibitory potencies of trimipramine and its main metabolites at human monoamine and organic cation transporters. | Haenisch, B., et al. 2011. Psychopharmacology (Berl). 217: 289-95. PMID: 21484238Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants. | Eap, CB., et al. 2021. World J Biol Psychiatry. 22: 561-628. PMID: 33977870Determination of trimipramine and its demethylated and hydroxylated metabolites in plasma by gas chromatography-mass spectrometry. | Eap, CB.Price of 2017188-77-9 , et al.1047991-79-6 web 1994.PMID:33674737 J Chromatogr. 652: 97-103. PMID: 8014234Increased trimipramine plasma levels during fluvoxamine comedication. | Seifritz, E., et al. 1994. Eur Neuropsychopharmacol. 4: 15-20. PMID: 8204992Safety of liver donation after fatal intoxication with the tricyclic antidepressant trimipramine. | Fattinger, KE., et al. 1996. Transplantation. 62: 1259-62. PMID: 8932268Quantitation of trimipramine enantiomers in human serum by enantioselective high-performance liquid chromatography and mixed-mode disc solid-phase extraction. | Liu, J. and Stewart, JT. 1997. J Chromatogr B Biomed Sci Appl. 700: 175-82. PMID: 9390727