Product Name :
Thyroid Hormone Receptor alpha Recombinant Rabbit Monoclonal Antibody [JE40-49]
Predicted band size :
55 kDa
Observed band size :
55 kDa
Synonyms:
AR7 antibody c-erbA-1 antibody C-erbA-alpha antibody CHNG6 antibody EAR-7 antibody EAR7 antibody ERB-T-1 antibody ERBA antibody ERBA-related 7 antibody ERBA1 antibody 展开
Function :
Thyroid hormone receptor alpha (TR-alpha) also known as nuclear receptor subfamily 1, group A, member 1 (NR1A1), is a nuclear receptor protein that in humans is encoded by the THRA gene. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Mutations of the THRA gene may cause nongoitrous congenital hypothyroidism-6, a subtype of congenital hypothyroidism.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human Thyroid Hormone Receptor alpha aa 416-465 / 490.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE40-49
RRID:
AB_3072776
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Buy1,7-Naphthyridin-3-amine Aliquot store at -20℃.Buy2-Ethylnicotinic acid Avoid repeated freeze / thaw cycles.PMID:33629229
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 55 kDa
Positive control :
A431 cell lysate, SW480 cell lysate.