Product Name :
PGP9.5 Recombinant Rabbit Monoclonal Antibody [JM10-59]
Predicted band size :
25 kDa
Observed band size :
25 kDa
Synonyms:
Epididymis luminal protein 117 antibody Epididymis secretory protein Li 53 antibody HEL 117 antibody HEL S 53 antibody NDGOA antibody Neuron cytoplasmic protein 9.5 antibody OTTHUMP00000218137 antibody OTTHUMP00000218139 antibody OTTHUMP00000218140 antibody OTTHUMP00000218141 antibody 展开
Function :
UCH-L1 (ubiquitin C-terminal hydrolase) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer.Formula of 6-Bromo-2-fluoro-3-methoxybenzoic acid Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1-2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p13. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PGP95 aa 191-223 / 223.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC, IHC-Fr
Coupling :
unconjugated
Clone number:
JM10-59
RRID:
AB_3070379
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.Formula of 1-Bromo-2-chloro-4,5-difluorobenzene
Storage buffer solution:
1*TBS (pH7.PMID:33601894 4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 25 kDa
Positive control :
A-172 cell lysate, SHG-44 cell lysate, U-87 MG cell lysate, SH-SY5Y cell lysate, NCI-H1299 cell lysate, A549 cell lysate, 293T cell lysate, Neuro-2a cell lysate, C6 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, N2A, PC-12, mouse spinal cord tissue, mouse skin tissue, mouse brain tissue, mouse colon tissue, mouse cerebrum tissue.