Product Name :
PDGF Receptor beta Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Beta platelet derived growth factor receptor antibody Beta-type platelet-derived growth factor receptor antibody CD 140B antibody CD140 antigen-like family member B antibody CD140b antibody CD140b antigen antibody IBGC4 antibody IMF1 antibody JTK12 antibody OTTHUMP00000160528 antibody 展开
Function :
Platelet-derived growth factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. These three isoforms bind with different affinities to two receptor types, PDGFR-α and -β, which are endowed with protein tyrosine kinase domains. PDGFR-α can bind to both A and B subunits of PDGF, while PDGFR- PDGF-AA induces the dimerization of αα and αβ and PDGF-BB induces the formation of three types of PDGF-AB induces dimerization of αα and αβ and PDGF-BB induces the formation of three types A dimlist, αα, αβ and ββ. Translocation of the PDGFR-β gene with the Tel gene is linked to chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrate the oncogenic potential of the PDGF receptors.BuyAminoethyl-SS-propionic acid
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within human PDGF Receptor beta aa 180-222.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3073352
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Buy1,8-Dihydroxynaphthalene Aliquot store at -20℃ or -80℃.PMID:33465489 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 124 kDa
Positive control :
Hela, HepG2, MCF-7, human spleen tissue, mouse brain tissue, NIH-3T3.