Ents had aneurysm PED therapy and six (19.4 ) individuals had additional or intracranial carotid angioplasty and stenting. There have been no substantial variations in the variety of individuals undergoing every procedure in between remedy groups. A total of eight (9.three ) hemorrhagic complications had been observed. Hemorrhages had been noticed in two (three.6 ) sufferers treated with aspirin/clopidogrel DAPT and in six (19.four ) patients treated with aspirin/prasugrel DAPT (p.02) (table two). Excluding one patient inside the aspirin/prasugrel DAPT group who experienced a basilar artery perforation, the difference in hemorrhage prices involving the DAPT groups trended towards significance but did not reach statistical significance (p.09). Inside the aspirin/clopidogrel group, hemorrhage was observed in one (33.three ) patient treated with Onyx aneurysm embolization and a single (14.3 ) patient treated with aneurysm PED placement. For the aspirin/prasugrel group, hemorrhagic events have been noticed in 1 (22.six ) patient treated with aneurysm coil embolization, one particular (12.5 ) patient treated with aneurysm stent assisted coil embolization, two (22.two ) individuals treated with aneurysm PED placement, one (33.three ) patient treated with extracranial carotid angioplasty and stenting, and one (50 ) patient treated with intracranial carotid angioplasty and stenting (table two). No statistically considerable differences in hemorrhage prices were observed in between treatment groups for every single procedure. There had been no significant variations within the rate of neurological (eg, intracerebral) and nonneurological (eg, extracerebral) hemorrhage among remedy groups (p0.13 in both cases). Inside the aspirin/clopidogrel group, one patient skilled a groin hematoma with retroperitoneal extension requiring a blood transfusion after Onyx embolization of a rightTablePatient demographics and procedures performedn 55 31 Gender (n ( )) 11 M (20) 44 F (80) 7 M (23) 24 F (77) Age (years) 61.2612.4 59.4614.8 0.565 Anx coil (n ( )) 17 (30.9) 5 (16.1) 0.198 Anx stent coil (n ( )) 22 (40.0) eight (25.eight) 0.241 Anx Onyx embo (n ( )) three (5.5) three (9.7) 0.663 Anx PED (n ( )) 7 (12.7) 9 (29.0) 0.084 Extracranial carotid angioplasty and stenting (n ( )) three (five.2,4-Dichlorofuro[3,2-d]pyrimidine Chemscene five) six (19.Formula of Methyl 2-(2-bromothiazol-4-yl)acetate four) 0.PMID:33481014 065 Intracranial carotid angioplasty and stenting (n ( )) two (3.six) 0 (0) e dAVF coil embo (n ( )) 1 (1.eight) 0 (0) eTreatment group Aspirin and clopidogrel Aspirin and prasugrel p ValueAnx, aneurysm; dAVF, dural arteriovenous fistula; embo, embolization; PED, pipeline embolization device.J NeuroIntervent Surg 2013;5:33743. doi:10.1136/neurintsurg2012Clinical neurologyTable two Hemorrhagic complications among treatment groupsTotal (n ( )) 2 (three.6) 6 (19.4) 0.02 Anx coil (n ( )) 0 (0) 1 (20) 0.24 Anx stent coil (n ( )) 0 (0) 1 (12.five) 0.27 Anx Onyx embo (n ( )) 1 (33.three) 0 (0) e Anx PED (n ( )) 1 (14.three) 2 (22.two) 1.0 Extracranial carotid angioplasty and stenting (n ( )) 0 (0) 1 (33.three) e Intracranial carotid angioplasty and stenting (n ( )) 0 (0) 1 (50) e dAVF coil embo (n ( )) 0 (0) 0 (0) eTreatment group Aspirin and clopidogrel Aspirin and prasugrel p ValueAnx, aneurysm; dAVF, dural arteriovenous fistula; embo, embolization; PED, pipeline embolization device.paraclinoid aneurysm. Another patient, treated with PED for a left cavernous carotid aneurysm, presented 5 days immediately after treatment with headache and was located to possess an anterior interhemispheric subarachnoid hemorrhage. Within the aspirin/prasugrel group, one particular patient had a basilar artery perforation with subarachnoid hemorrhage, intraventricular he.
