Product Name :
p53 Rabbit Polyclonal Antibody
Predicted band size :
44 kDa
Observed band size :
53 kDa
Synonyms:
Antigen NY-CO-13 antibody BCC7 antibody Cellular tumor antigen p53 antibody FLJ92943 antibody LFS1 antibody Mutant tumor protein 53 antibody p53 antibody p53 tumor suppressor antibody P53_HUMAN antibody Phosphoprotein p53 antibody 展开
Function :
The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. P53 is found in increased amounts in a wide variety of transformed cells. P53 is frequently mutated or inactivated in about 60% of cancers.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within C-terminal human P53.
Species reactivity:
Human
Verify application:
WB, IF-Cell
Coupling :
unconjugated
Clone number:
RRID:
AB_3073237
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1810068-31-5 Order Aliquot store at -20℃ or -80℃.5-Bromo-3-nitropyridine-2-carbaldehyde Purity Avoid repeated freeze / thaw cycles.PMID:33569611
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 53 kDa
Positive control :
MDA-MB-231 cell lysate, HEK-293 cell lysate, MDA-MB-468 cell lysate, A431.