Product Name :
TGIF Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
5′ TG 3′ interacting factor antibody 5”-TG-3”-interacting factor 1 antibody Homeobox protein TGIF antibody Homeobox protein TGIF1 antibody HPE4 antibody MGC39747 antibody MGC5066 antibody TALE homeobox TG-interacting factor antibody TG interacting factor isoform c antibody TG-interacting factor antibody 展开
Function :
The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provide
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from the C-terminal region of human TGIF.85272-31-7 site
Species reactivity:
Human, Mouse, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1214824-64-2 site Aliquot store at -20℃ or -80℃.PMID:33689157 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
43 kDa
Positive control :
Brain,Liver,Placenta,