Product Name :
PLGF Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
D12S1900 antibody Pgf antibody PGFL antibody PIGF antibody Placenta growth factor antibody Placental growth factor antibody Placental growth factor, vascular endothelial growth factor related protein antibody PlGF 2 antibody PlGF antibody PLGF_HUMAN antibody 展开
Function :
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations.Formula of 3-Bromo-6-fluoropicolinic acid Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human PLGF aa 11-161 / 221.
Species reactivity:
Human, Mouse
Verify application:
IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069097
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1820570-42-0 web Aliquot store at -20℃ or -80℃.PMID:33674217 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 25 kDa
Positive control :
Human kidney tissue, mouse testis tissue, SH-SY5Y.